Vasso Apostolopoulos, PhD Professor

Email: [email protected]


LAST UPDATE: 2014

    Vasso Apostolopoulos - Latest News

Katsara, M., Grigoriadis, N., Yuriev, E., Ramsland, P.A., Deraos, G., Matsoukas, J. and Apostolopoulos, V. Helani Congress, Athens, Greece, October 2013. Mannosylation of mutated MBP83-99 peptides diverts immune responses from Th1 to Th2 in SJL/J mice: Bioactive peptides for Multiple Sclerosis
LATEST CONFERENCE POSTER PRESENTATIONS

Perera, C.J., Zahrooni, S., Apostolopoulos, V. and Moalem-Taylor, G. 4th International congress on neuropathic pain: The pain to relief starts with understanding. Toronto, Canada. May 2013. Immunisation with myelin-derived altered peptide ligands inhibits neuropathic pain following peripheral nerve injury
Perera, C.J., Zahrooni, S., Apostolopoulos, V. and Moalem-Taylor, G. Australian Neuroscience Society, Melbourne Australia. February 2013. Vaccination for neuropathic pain following peripheral nerve injury
LATEST PUBLICATIONS


Kong, Y.Y., Fuchsberger, M., Xiang, S.D., Apostolopoulos, V. and Plebanski, M. Myeloid-Derived Suppressor Cells and their role in diseases. Current Medicinal Chemistry, 20(11):1437-1444, 2013. [Corresponding author].ong, Y.Y., Fuchsberger, M., Xiang, S.D., Apostolopoulos, V. and Plebanski, M. Myeloid-Derived Suppressor Cells and their role in diseases. Current Medicinal Chemistry, 20(11):1437-1444, 2013. [Corresponding author].

Apostolopoulos, VInterview. Cancer Vaccines: Looking to the future. Expert Review of Vaccines, 12(10):1125-1126, 2013. [Invited].



Gartlan, K.H., Wee, J.L., DeMaria, M.C., Nastovska, R., Chang, T.M., Jones, E.L., Apostolopoulos, V., Pietersz, G.A., Hickey, M.J., van Spriel, A.B. and Wright, M.D. Tetraspanin CD37 contributes to the initiation of cellular immunity by promoting dendritic cell migration. European Journal of Immunology, 43(5):1208-1219, 2013.

Cover Image on EJI of Gartlan et al article: The cover features a digitally-coloured scanning electron microscopy image of CD37-deficient dendritic cells (DCs) stimulated with lipopolysaccharide. The image is taken from the article by Gartlan et al. (pp. 1208–1219) in which the authors show that DC adherence to fibronectincoated coverslips is impaired in the absence of the tetraspanin CD37. Gartlan et al. further show that ablation of CD37 in mice also impairs DC migration from skin to draining lymph nodes, chemotactic migration and priming of naive T cells. Together, these findings support a role for CD37 in cellular immunity by promoting DC migration.  Well Done Kate on excellent work and for the cover of EJI......!
Sheng, K.C., Day, S., Wright, M.D., Stojanovska, L. and Apostolopoulos, V. Enhanced dendritic cell-mediated antigen-specific CD4+ T cell responses: IFN-gamma aids TLR stimulation. Journal of Drug Delivery, Volume 2013, Article ID 516749, Epub May 28 2013. [Corresponding author].

Apostolopoulos, V., Thalhammer, T., Tzakos, A.G. and Stojanovska, L. Targeting antigens to dendritic cell receptors for vaccine development, Volume 2014, Article ID869718, Epub October 2013. [Corresponding author]

Tian, D.H., Perera, C.J., Apostolopoulos, V. and Moalem-Taylor, G. Effects of vaccination with altered peptide ligand on chronic pain in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis. Frontiers in Neurology – Multiple Sclerosis and Neuroimmunology. 4(168):1-8, October 2013.
Molecular model of APL peptide MBP85-96 [Y91] in complex with MHC class II H2 I-As. From Katsara and Apostolopoulos et al.,
Schematic representation of MBP83-99 peptide in complex with HLA-DR2. From Katsara and Apostolopoulos et al.,
Crystal structure of MHC class I in complex with peptide and TcR. From Lazoura and Apostolopoulos et al.,
Structure of MUC1 GalNAc peptide in complex with MHC class I. From Lazoura and Apotolopoulos et al.,
Novel Oncology Therapeutics: Targeted Drug Delivery for Cancer

Guest Editors: 
Andreas Tzakos, Evangelos Briasoulis, Theresia Thalhammer, Walter Jäger, Vasso Apostolopoulos 
12 Articles and 1 Editorial, October 2013. Link
GUEST EDITOR, Special Issue
Editorial. Tzakos, A..G., Briasoulis, E., Thalhammer, T., Jager, W. and Apostolopoulos, V. Novel Oncology Therapeutics: targeted drug delivery for cancer. Journal of Drug Delivery, Volume 2013, Article ID 918304, Epub October 2013. PDF
Vassilaros, S., Tsibanis, A., Tsikkinis, A., McKenzie, I.F.C and Apostolopoulos, V. Up to 15 year clinical follow-up of pilot phase III immunotherapy study in stage II breast cancer patients using oxidised mannan-MUC1. Immunotherapy, 5(11):1177-1182, 2013.

Stojanovska, L. and Apostolopoulos, V. Trick or treat? Alternative therapies for menopause. The Conversation, Published 13 February 2014, Article No. 18007, 2014. Link
Stojanovska, L., Apostolopoulos, V., Polman, R. and Borkoles, E. To exercise, or, not to exercise, during menopause and beyond. Maturitas, 77(4):318-323, 2014
Apostolopoulos, V. 5th Australasian vaccines and immunotherapeutics development (AVID) meeting. Melbourne VIC Australia, May 2014. Clinical study in stage II breast cancer patients using oxidised mannan-MUC1: clinical data 16.5 years on